I have exactly the same problem. I updated the following things (note: i dont have the pinpoint plugin, so this might have nothing to do with it):
WordPress to 4.3
Cardinal Theme to 2.22
Swift Framework to 1.51
Contact Form 7 to 4.2.2
As you mentioned, the Page Builder doesn’t load, and the button to switch is not responsive. I will try to delete and reinstall the Swift Framework later tonight. I’ll let you if this works. In the mean time, any help is welcome!
Joris.